John has realized where the demon will strike next and the Winchesters head there to stop the next killing. But Meg begins killing John's friends and demands the Colt. ..More

When Meg boasts that John is her prisoner, the boys visit a friend of their father's to get information about demonic possessions and ways to trap a demon. It turns out Meg is not what she appears. ..More

Sam and Dean meet Andy Gallagher, a slacker with psychic powers of persuasion. Once the brothers learn that Andy's family was visited by the Demon, Sam wonders if he could be one of the special children. ..More

Sam and Dean investigate the slayings of blonde women and find that the ghost of the first known serial killer in US history is responsible. Jo disobeys Ellen's wishes and follows them along, and is captured by the ghost. ..More

Sam and Dean investigate the murder of a lawyer and his wife, who claimed to have seen a ghost before they were killed. However, local authorities arrest the Winchesters after looking into their past. ..More

Sam has a vision of Dean shooting a defenseless man, and they go to the town of River Grove, where they find the townspeople have been possessed by a virus that makes them violent. ..More

Sam meets a woman who shares his ability to have visions, and she warns him that she has seen the future... where he dies in an explosion. ..More

Sam and Dean investigate a Connecticut inn run by a single mother where mysterious deaths are taking place. They find evidence of Hoodoo, and try to figure out who is causing the chaos. ..More

The Winchesters investigate a series of crimes where robbers with no criminal past commit suicide after the hold-ups. ..More

Dean refuses Sam's efforts to help him battle the Devil, and then wakes up to find himself five years in the future, in a wasteland where Lucifer has begun his endgame by unleashing a virus that transforms humans into zombies. ..More