Sam and Dean investigate a girl's death that may be linked to a ghost. Their probe leads them to encounter Harry and Ed, two famous supernaturalists, who are also on the case.
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Sam and Dean get help from a former member of the Men of Letters to locate the First Blade, after Crowley falls off the wagon and starts injecting himself with human blood.
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Tessa the reaper returns and leads a conspiracy against Castiel's angel followers. Meanwhile, Dean is eager to use the First Blade when the angels are attacked, but Sam worries about the cost to his brother whenever he uses it.
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Dean becomes more aggressive as a demon, and Crowley tells him it's because the Mark of Cain needs to be fed. Meanwhile, Sam is captured by an angry man who blames Dean for his father's death and wants revenge.
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Sam tries to release Dean from the Mark of Cain. Meanwhile, Crowley seeks the help of an unlikely ally after encountering problems due to Dean's behavior.
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Rowena returns and tries to recruit and train followers in the art of witchcraft, but Sam & Dean devise a plan to stop her. Meanwhile, Hannah runs into a blast from her vessel's past, which complicates things for her and Castiel.
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Jody Mills reluctantly attends a mandatory Sheriff's retreat and is partnered with an overeager sheriff who wants to bond. A body with just strings of meat and skin hanging off the bones is discovered. Jody calls Sam and Dean for help.
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ABOUT
Twenty-six years ago, Sam Winchester and Dean Winchester lost their mother to a mysterious and demonic supernatural force. Subsequently, their father John raised them to be soldiers. He taught them about the paranormal evil that lives in the dark corners and on the back roads of America ... and he taught them how to kill it.
