Fine (James Marsters) unleashes a virus that could kill millions of people and refuses to give Clark the vaccine unless he agrees to release the spirit of an imprisoned Kryptonian criminal. Clark turns to Lionel, who once again channels Jor-El (voiced by Terence Stamp). Meanwhile, Lex is stunned by his newfound powers and shares the discovery with Lana, who decides to stand by her new man, unaware of the shocking turn Lex's life is about to take.

Season 5 | Episode 22

Allison Mack

Chloe Sullivan

Annette O'Toole

Martha Kent

Erica Durance

Lois Lane

John Schneider

Jonathan Kent

Kristin Kreuk

Lana Lang

Michael Rosenbaum

Lex Luthor

Tom Welling

Clark Kent